Interestingly, according to the guy from the Lebanon Daily News (see thread elsewhere on that), PSU made
exactly that adjustment for the MSU game. With a fair amount of success (I quote):
"As for the number, Hackenberg finished
20 of 27 for 249 yards, two touchdowns and a tipped interception on passes released in less than 2.3 seconds from snap to throw."
but
"When Hackenberg was forced to hold on to the ball, and consequently was under pressure, his numbers fell to a horrid
2 of 12 for eight yards and an interception."
See
this link for more.
Of course, 4 turnovers will ruin your day. If I am not mistaken, all 4 went for TD's eventually. That accounts for a lot of the magnitude of the loss. At least two of those are not the fault of coaching.