Latka and Jim were 2 of the funniest characters ever IMO. Kramer is my FOAT.I think Taxi had some great unique comic talent. Kaufman was just off the wall. Devito was a great fit for his role. I think the episode when Christopher Lloyd in a flashback sequence,fries his brain eating a hash brownie when he was a student at Harvard might be one of the funniest 5 minutes of comedy I remember. A little tibit of the scene, his college roommate at Harvard was played by an unknown actor at the time, Tom Hanks.
I probably should've had Eastbound and Down on my list. Danny McBride is one of the funniest humans on the planet. The Righteous Gemstones isn't quite as good, but still excellent.A lot of good ones already mentioned
One though that hasn’t been brought up yet is Eastbound and Down.