Has anyone used 23andme dna tests....

Discussion in 'BWI / McAndrew Board' started by RandyL, May 31, 2018.

  1. 83wuzme

    83wuzme Well-Known Member
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    I can see insurers being interested in this information : life, disability, long term care, etc. It doesn’t require a genius to understand how these coverages could be affected by a person’s genetic makeup. Who knows, maybe at some point in time genetic testing could be an approval condition for underwriting.
    A potential mate might want to know about this information as well.
     
  2. PSU_sues_ncaa_big10

    PSU_sues_ncaa_big10 Well-Known Member
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    This data is worth so much and people are PAYING the company to take it!
     
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  3. NittanyLionFan

    NittanyLionFan Well-Known Member
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    On AncestryDNA, anyone that takes their test is matched against others that have taken the test and, if there is sufficient shared DNA, a cousin match is estimated (i.e., 1st cousin, 4th cousin... I think the most distant it will project is 5-8th cousin). If you take their test, you can view these matches. I assume that you can opt out of having your results, to include potential matches, visible. Your match will only display a self-designated user name and other details you care to share. It will also share your public family tree, if you have one (only people that are marked as deceased will be visible and only if your tree is public, not private). If you have it linked to your tree, the site can also analyze both trees (if public) and project the common ancestor. Pretty neat. Ancestry also has a built-in user messaging system (again, you only see user name); that is typically how you first contact another user. It is a pretty basic system, so you don't know if they've read your message, etc.

    I am not 100% sure of how it works for non (paying) subscribers. I think that you can view your results and potential cousins, but can only receive but not send messages (so I usually include my email address when I send a message). My father in law is in that boat, and I am pretty sure that he has received messages from potential cousins (and then he either takes the conversation to email or asks me to send a response to the other user!). That side of the family has a "baby on the porch" story from the 1880s and has been getting hits to potential cousins with the suspected biological surname (family lore), but no exact connections have yet been made...
     
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  4. RandyL

    RandyL Well-Known Member
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    mucho gracias
     
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  5. Wandering Spectator

    Wandering Spectator Well-Known Member
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    I use both. My main purpose is to identify the origin of my Italian surname. My Great grandfather came to the US in 1881 (pre Ellis Island) and originated the surname I have today. No other family in the world has it. Everyone with my surname tracks back to him. Through these services, I am able to ID “cousins” via the DNA, then I trace their families to help build the tree. I’m getting closer to identifying his origin but I’m not there yet.

    There are definite concerns though as well. I recently was alerted to a very close cousin match that just received his results. When I reached out to him, I learned he was adopted. He’s likely a son of one of my first cousins.... This is going to get very interesting.
     
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  6. hagberg

    hagberg Well-Known Member
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    Dang, those things really are a scam!
     
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  7. RandyL

    RandyL Well-Known Member
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    In Yuval Noah Harari’s book “Sapiens”, he points out that even today, humans originating from the Middle East or Europe still contain a small % of neanderthal dna.
    A short while ago, I mentioned to a group of women that most men still contain some neanderthal in them.
    They did not seem surprised.
     
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  8. MontereyLion

    MontereyLion Well-Known Member
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    There is some debate about that.
     
  9. NittanyLionFan

    NittanyLionFan Well-Known Member
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  10. LionDeNittany

    LionDeNittany Well-Known Member
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    Yeah but the problem with this argument is like not giving away your phone number.

    It doesn't matter if you keep it amongst just a few people. One of those people will allow a service to see all their contacts, and voila.

    Once a few family members give up their DNA, yours is known.

    LdN
     
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  11. JWB389

    JWB389 Well-Known Member
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    Centex, we had a similar experience. Both my wife and daughter had been diagnosed with celiac a few years ago. My daughter's 23 & me came back with a high probability of celiac. Of course, we already knew that, but it was a an interesting verification. You may already know this, but either you or your wife/daughter's mom are carriers. Several people on my wife's mother's side of the family have it.

    Funny story, the husband of a co-worker got a call a few months ago with a surprise from a 20 something daughter in Oklahoma he didn't know he had. Not a bad story. A woman he dated prior to his wife. She found out several weeks after they drifted apart. Decided to keep the baby. The kid gets a 23 & Me that matches her to an Aunt. She contacts the aunt, yadda yadda....she connects to the dad.
     
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  12. Nitwit97

    Nitwit97 Well-Known Member
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    Point well taken. But my parents are too old to be into it and my kids are not old enough to do it themselves. I am in the “sweet spot”
     
  13. CentexLion

    CentexLion Well-Known Member
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    Great story about the co-worker. I was hiking in Colorado a month ago a met a person with a similar situation. 50+ year guy had a call from a daughter (30) that he never knew about. His wife is cool with it, but his sister was having a hard time accepting it.

    23-and-me flagged me as the having one of the two genes for celiac, so I'm certain to have past that to my daughter, who has a big reaction to gluten. When she is home with us, we all go gluten free and I certainly can feel it helping me a small bit. I believe my dad also has it a bit, but there is no way he is giving up wheat (and my mom doesn't know how to cook without wheat products). That said, we are finding a few great Gluten free places. A British place outside of Keller Texas (she is doing a medical internship there) with great GF food. Fish and Chips were awesome. Best place is north of Cypress TX. Farm to Market place. Best GF bread I ever had and ranks up with some of the best bread ever.

    Biggest downfall is beer. No top of the line GF beer. I think I've tried them all. Greene is OK. Suneater is OK. Clear and Free is OK. Nothing like any of the craft beer places around though.

    Good luck on your end there. Not an easy thing to deal with, especially when traveling, but it is getting easier.
     
  14. LionDeNittany

    LionDeNittany Well-Known Member
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    You dont have cousins neices or aunts and uncles?

    They matched me with my mothers sister.

    Again. Totally independent submission.

    LdN
     
  15. JWB389

    JWB389 Well-Known Member
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    Thanks and good luck to you as well. Very mysterious the way it's so prevalent now. Unfortunately, my wife gets very ill too.

    There are a lot of great places here in Eastern PA for GF. All the major chains make it easy to find SOMETHING you can eat. Still very difficult to deal with, particularly for a little kid that's into everything little kids are into. End of year parties, etc. Everybody has to have a cake and cookies.

    Other than beer and occasional pasta (I keep a separate pot for it) for me, our house is gluten free. I've never tried anything other than Redbridge and I wasn't impressed. Some of the cider's are OK and the new spiked sparkling waters are good.

    The bread is what we struggle with the most. Cannot find a good one. Maybe your TX connection could hook up with somebody in eastern PA!
     
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  16. CentexLion

    CentexLion Well-Known Member
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    I'm heading back to Schnecksville and Northampton in September for a nephews wedding. You'll have to let me know the better GF places.
     
  17. JWB389

    JWB389 Well-Known Member
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    Great brew pub (I think it's a small chain) BJ's Brewhouse in the west end of Allentown, just before Wescosville. They do a very good job.
    https://www.bjsrestaurants.com/menu

    Mesa Mexican in downtown Easton is really good too.
    http://mesamexican.com/

    If you head east onto Clinton, NJ another fantastic place is The Clean Plate Kitchen. Or even farther into NJ - Hackettstown has Mama's. Excellent for everybody.

    Outside of that, mostly big chains.

    Forgot to mention this https://nimasensor.com/?gclid=EAIaIQobChMIi42ay6uz2wIVhouzCh38zQ4KEAAYASAAEgIFVPD_BwE

    Just got one for my wife. It seems to work.
     
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  18. 83wuzme

    83wuzme Well-Known Member
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    The average DNA differences between present human populations and the Neanderthal sequences we have sequenced so far is something around 0.12- 0.15 %. So it’s a bit misleading when you would get a result saying you’re “ 2.5 % Neanderthal “. All out of Africa ancestral populations have some Neanderthal - derived sequences.
    Neanderthals were large - brained, but they were short, stocky, ugly hairy, dangerously inbred and probably smelly. So yeah, I can see how women would recognize the Neanderthal in many men.
     
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  19. manatree

    manatree Well-Known Member
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  20. lein

    lein Well-Known Member
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    Wasn't there a story about identical twins sending their DNA to one of these companies and the results came back different?
     
  21. MJG-90

    MJG-90 Well-Known Member
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    For anyone near Mount Joy PA desiring gluten free baked goods, there is a fantastic little bakery on the west end of main street.

    https://www.madewithlovenotgluten.com/

    Make your own bread. I just made a keto / collagen bread from a recipe I found on blog.bulletproof.com.

    https://blog.bulletproof.com/keto-collagen-bread-recipe-3c/

    Just look around. A lot of recipes are pretty simple and quite tasty.
     
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  22. Wandering Spectator

    Wandering Spectator Well-Known Member
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    I not an expert in this, but it's my understanding that the "ancestry" results can be different due to how they analyze the DNA - not that the DNA is different. I didn't see the story you mentioned, but it's likely that they identified the twins as such, but each could potentially have different ancestry. Like anything, there are anomalies, and of course, the media will look for a story. For me, both 23andMe and Ancestry are helping to solve a mystery in my Italian origin. Very cool stuff.
     
  23. interrobang

    interrobang Well-Known Member
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    Of all places, Aldi has a great gluten free bread line called liveGFree.
     
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  24. interrobang

    interrobang Well-Known Member
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  25. GregInPitt

    GregInPitt Well-Known Member
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    Do you have reason to believe your DNA is compromised?
     
  26. interrobang

    interrobang Well-Known Member
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  27. massimoManca II

    massimoManca II Well-Known Member
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    Since this thread was originally posted, i found out about a consequence of 23-and-me while attending a family wedding this summer, might surprise some, maybe not :

    Uncle Ed tells me he submitted for a 23-and-me analysis in the spring... gets his results confirming we are a little more than 21st century gypsies from the Carpathian Mountains... then ends up being contacted by a 30yr old gal, turns out she had been given up for adoption in 1988 by my brother and his girlfriend while he was in med school.... ooopsie.

    #catsouttathebag
     
  28. PeetzPoolBoy

    PeetzPoolBoy Well-Known Member
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    You’ll only have yourself to blame if you ever get denied health care coverage after doing this.
     
  29. Delco Lion

    Delco Lion Well-Known Member
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    These tests show I am 1/8 Lenape Indian.
     
  30. JJTopp99

    JJTopp99 Well-Known Member
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  31. PeetzPoolBoy

    PeetzPoolBoy Well-Known Member
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    So when you register for 23andme, you have to share your contact information such that complete strangers can compare their DNA to yours and then can contact you? Why would anyone ever share real contact information?

    This is worse than I thought.
     
  32. massimoManca II

    massimoManca II Well-Known Member
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    Not sure if you can opt-out of having contact info disclosed, as such I’m not so sure if my uncle elected accordingly... all I know is that a 30yr old adopted woman has gotten to know a lot about her biological family, which is actually pretty cool...

    but some of you
    may shudder at the possibility/likelihood of a flashlight being shined on past decisions
     
  33. JJTopp99

    JJTopp99 Well-Known Member
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    No, the Ancestry pay site is separate from the genetic testing. And yes, the Ancestry genetic testing part of the website does provide names of relatives assuming the other parties (your cousins) used their real names...some people want to remain anonymous. Ancestry usually gives you the option to attempt to contact a relative they ID via their website ( although I believe people can opt out of this? ). Of course, it is up to the other party to decide whether they want to respond to your inquiry.

    Ancestry only provides the countries in which your cousins are located, not specific addresses. I had more than 13,000 matches of people possibly related to me (they give you a confidence level of that person being related to you using a bar graph). Several first and second cousins (people I've known for many decades) were identified correctly. And no, I did not know beforehand that any of them had had this genetic testing completed. I found it slightly humorous to learn I have a possible relative in England whose last name is Trump.

    A couple of distant relatives never responded to my wife's attempt to communicate with them. Most, however, did respond to her request for additional info.

    My wife and I do not pay to subscribe to the regular Ancestry account by the way.
     
    73 JJTopp99, Oct 11, 2018
    Last edited: Oct 11, 2018
  34. PeetzPoolBoy

    PeetzPoolBoy Well-Known Member
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    No kidding. Hopefully your brother informed his spouse of said former child and that crazy Uncle Ed didn’t drink too much at a family function and spill previously unknown beans.

    That would be really awkward.
     
  35. JJTopp99

    JJTopp99 Well-Known Member
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    Not so, there are many "opt out" options. You can provide a picture of yourself if you want to do so. You can use a false name or remain anonymous. You do not have to reply to anyone attempting to contact you (they can only contact you through the website unless you give them additional contact INFO of course). They cannot "compare" your DNA with theirs, they are only told that you are a possible relative, with a confidence level provided (Ancestry). Ancestry provides a bar graph of the confidence level of two people being related and 23 and Me provides a percentage of DNA shared.
     
    75 JJTopp99, Oct 11, 2018
    Last edited: Oct 11, 2018
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  36. massimoManca II

    massimoManca II Well-Known Member
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    All it takes is a dopey relative who submits for one of these tests....
     
  37. JJTopp99

    JJTopp99 Well-Known Member
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    ...or finding out you are a direct descendant of Hitler. A guy my wife works with found out he is a close relative of Tito, lol.

    I read somewhere that the current testing is only accurate going back seven generations. IDKW that is, or if that is actually true.
     
  38. massimoManca II

    massimoManca II Well-Known Member
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    Tito Jackson is a little bit better than Hitler :p
     
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  39. JJTopp99

    JJTopp99 Well-Known Member
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    Well, I'm just one "data" point but in my case the results I got from Ancestry and 23 and Me matched up closely. The results were pretty much what I expected.
     
  40. JJTopp99

    JJTopp99 Well-Known Member
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